2021年3月circRNA研究汇总-1（ 20210301-0307）

序号

主要内容

论文标题

杂志

影响因子

单位

1

环状RNA编码的致癌性E-钙粘着蛋白变体通过激活EGFR-STAT3信号传导促进胶质母细胞瘤致瘤性

Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR-STAT3 signalling

Nat Cell Biol.

20.042

中山大学附属第一医院等

2

通过抑制CircRNA-FoxO1靶向脉络膜血管功能障碍，可预防和管理近视

Targeting Choroidal Vascular Dysfunction via Inhibition of CircRNA-FoxO1 for Prevention and Management of Myopic Pathology

Mol Ther.

8.986

复旦大学附属眼耳鼻喉科医院等

3

circCAMSAP1通过海绵吸附miR-145-5p调节FLI1表达来促进骨肉瘤的进展和转移

circCAMSAP1 promotes osteosarcoma progression and metastasis by sponging miR-145-5p and regulating FLI1 expression

Mol Ther Nucleic Acids.

7.032

浙江省邵逸夫医院等

4

环状RNA Calm4通过Circ-Calm4 / miR-124-3p / PDCD6轴调节低氧诱导的肺动脉平滑肌细胞凋亡。

Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis

Arterioscler Thromb Vasc Biol.

6.604

哈尔滨医科大学等

5

环状RNA circGLIS3通过miR-1273f / SKP1 / Cyclin D1轴促进膀胱癌的增殖

Circular RNA circGLIS3 promotes bladder cancer proliferation via the miR-1273f/SKP1/Cyclin D1 axis

Cell Biol Toxicol.

6.284

温州医科大学等

6

非编码RNA在头颈癌放疗敏感性和耐药性中的作用：从基础研究到临床应用信息化

Role of Non-coding RNAs on the Radiotherapy Sensitivity and Resistance of Head and Neck Cancer: From Basic Research to Clinical Application

Front Cell Dev Biol.Review

5.201

中国医科大学附属盛京医院等

7

外泌体hsa_circ_0006859是绝经后骨质疏松症的潜在生物标志物，通过使miR-431-5p海绵化，可增强人骨髓间充质干细胞的成脂与成骨分化

Exosomal hsa_circ_0006859 is a potential biomarker for postmenopausal osteoporosis and enhances adipogenic versus osteogenic differentiation in human bone marrow mesenchymal stem cells by sponging miR-431-5p

Stem Cell Res Ther.

5.116

苏州大学附属第三医院等

8

circRNA CDR1as在肿瘤进展中的预后和预测意义

The Prognostic and Predictive Significance of circRNA CDR1as in Tumor Progression

Front Oncol.

4.848

徐州市中心医院等

9

环状RNA对人类癌症宿主基因的调控作用

Regulatory Effects of Circular RNAs on Host Genes in Human Cancer

Front Oncol.Review

4.848

武汉同济医院等

10

Circ-LAMP1通过miR-556-5p和miR-567介导的YY1激活促进胆管癌的生长和转移

Circ-LAMP1 contributes to the growth and metastasis of cholangiocarcinoma via miR-556-5p and miR-567 mediated YY1 activation

J Cell Mol Med.

4.486

哈尔滨市第二医院等

11

环形RNA circCSPP1敲低可以通过miR-944 / FZD7轴减弱阿霉素抗性并抑制大肠癌的肿瘤进展

Circular RNA circCSPP1 knockdown attenuates doxorubicin resistance and suppresses tumor progression of colorectal cancer via miR-944/FZD7 axis

Cancer Cell Int.

4.175

河南郑州肛肠医院等

12

RNA测序揭示了circRNA的表达谱，并鉴定了四个circRNA信号充当食管鳞状细胞癌的预后标记

RNA sequencing reveals the expression profiles of circRNA and identifies a four-circRNA signature acts as a prognostic marker in esophageal squamous cell carcinoma

Cancer Cell Int.

4.175

郑州大学第一附属医院等

13

体积小，但作用大：microRNA作为乳腺癌和肺癌中PTEN的潜在调节剂

Small in Size, but Large in Action: microRNAs as Potential Modulators of PTEN in Breast and Lung Cancers

Biomolecules.Review

4.082

新加坡国立大学永禄林医学院等

14

circUBAP2通过miR’204′.3p / HMGA2轴调节骨肉瘤的进展

circUBAP2 regulates osteosarcoma progression via the miR‑204‑3p/HMGA2 axis

Int J Oncol.

3.899

河南省肿瘤医院等

15

外泌体环状RNA在肿瘤中的潜在转移机制及临床应用（综述）

Underlying metastasis mechanism and clinical application of exosomal circular RNA in tumors (Review)

Int J Oncol.

3.899

中国医科大学附属盛京医院等

16

Circ_0000511通过miR-326 / TAZ轴促进乳腺癌细胞的增殖，迁移和侵袭并抑制其凋亡

Circ_0000511 accelerates the proliferation, migration and invasion, and restrains the apoptosis of breast cancer cells through the miR-326/TAZ axis.

Int J Oncol.

3.899

吉林大学第一医院等

17

环状RNA的设计与合成

The Design and Synthesis of Circular RNAs

Methods.

3.812

耶鲁大学医学院等

18

Thrown for a (stem) loop: RNA结构如何影响环状RNA调节和功能

Thrown for a (stem) loop: how RNA structure impacts circular RNA regulation and function

Methods.

3.812

约翰·霍普金斯大学等

19

环状RNA circ_0079593通过调节miR-573 / ABHD2轴增强恶性黑色素瘤进展

Circular RNA circ_0079593 enhances malignant melanoma progression by the regulation of the miR-573/ABHD2 axis

J Dermatol Sci.

3.681

河北医科大学等

20

环状RNA circVAPA通过调节miR-125b-5p / STAT3轴促进胃癌进展中的化疗药物耐药性

Circular RNA circVAPA promotes chemotherapy drug resistance in gastric cancer progression by regulating miR-125b-5p/STAT3 axis

World J Gastroenterol.

3.665

中国医科大学附属第一医院等

21

心脏猝死相关疾病中的环状RNA：用于临床和法医诊断的新型生物标志物

Circular RNAs in Sudden Cardiac Death Related Diseases: Novel Biomarker for Clinical and Forensic Diagnosis

Molecules.Review

3.267

中国医科大学法医学遗传学系等

22

复发性植入失败的环状RNA–MicroRNA–Messenger RNA调控网络的构建以探讨其潜在发病机理

Construction of Circular RNA-MicroRNA-Messenger RNA Regulatory Network of Recurrent Implantation Failure to Explore Its Potential Pathogenesis

Front Genet.

3.258

大理大学生殖医学研究所等

23

动脉粥样硬化中不同表达的mRNA的鉴定揭示了CDK6受circHIPK3 / miR-637轴调控，并促进人血管平滑肌细胞的细胞生长。

Identification of Differently Expressed mRNAs in Atherosclerosis Reveals CDK6 Is Regulated by circHIPK3/miR-637 Axis and Promotes Cell Growth in Human Vascular Smooth Muscle Cells

Front Genet.

3.258

复旦大学附属中山医院等

24

鸡生长激素受体基因环状RNA对细胞增殖的影响

Effects of Circular RNA of Chicken Growth Hormone Receptor Gene on Cell Proliferation

Front Genet.

3.258

广东海洋大学等

25

Aloperine通过调节circNSUN2 / miR-296-5p / STAT3途径抑制大肠癌细胞的增殖并促进其凋亡

Aloperine Inhibits Proliferation and Promotes Apoptosis in Colorectal Cancer Cells by Regulating the circNSUN2/miR-296-5p/STAT3 Pathway

Drug Des Devel Ther.

3.216

南京市中医院等

26

环状RNA表达在脊髓损伤后病理过程中的作用

Role of circular RNA expression in the pathological progression after spinal cord injury

Neural Regen Res.

3.171

四川大学华西医院等

27

CircPRKCI通过靶向miR-219a-5p调节的CAMK1D来调节肺腺癌细胞的增殖，迁移和周期

CircPRKCI regulates proliferation, migration and cycle of lung adenocarcinoma cells by targeting miR-219a-5p-regulated CAMK1D

Eur Rev Med Pharmacol Sci.

3.024

烟台毓璜顶医院等

28

环状RNA circSOX4通过下调microRNA-432表达促进肝癌细胞的增殖，迁移和凋亡

Circular RNA circSOX4 promotes the proliferation, migration and apoptosis of hepatocellular carcinoma cells by down regulating microRNA-432 expression

Eur Rev Med Pharmacol Sci.

3.024

聊城市人民医院等

29

环状RNA circVMA21通过靶向脓毒症中的miR-199a-5p / NRP1轴改善了脂多糖（LPS）诱导的急性肾脏损伤

Circular RNA circVMA21 ameliorates lipopolysaccharide (LPS)-induced acute kidney injury by targeting the miR-199a-5p/NRP1 axis in sepsis

Biochem Biophys Res Commun.

2.985

山西省人民医院等

30

套筒胃切除术后从糖尿病大鼠中发现的环状RNA circDOCK7的下调通过调节miR-139-3p和MCM3促进肝细胞凋亡

Downregulation of circular RNA circDOCK7 identified from diabetic rats after sleeve gastrectomy contributes to hepatocyte apoptosis through regulating miR-139-3p and MCM3

Biochem Biophys Res Commun.

2.985

山东省千佛山医院等

31

外泌体circ_IFT80通过调节miR-296-5p / MSI1轴增强结直肠癌的肿瘤发生并抑制放射敏感性

Exosomal circ_IFT80 Enhances Tumorigenesis and Suppresses Radiosensitivity in Colorectal Cancer by Regulating miR-296-5p/MSI1 Axis

Cancer Manag Res.

2.886

中山大学附属第七医院等

32

环状RNA circSPATATA6通过miR-182调节TRAF6抑制口腔鳞状细胞癌细胞的发展

Circular RNA circSPATA6 Inhibits the Progression of Oral Squamous Cell Carcinoma Cells by Regulating TRAF6 via miR-182

Cancer Manag Res.

2.886

内蒙古包钢医院等

33

c-Myc诱导的circ-NOTCH1通过调节miR-34c-5p / c-Myc轴促进鼻咽癌细胞的侵袭性表型

c-Myc-induced circ-NOTCH1 promotes aggressive phenotypes of nasopharyngeal carcinoma cells by regulating the miR-34c-5p/c-Myc axis

Cell Biol Int.

2.571

江苏省中医院等

34

CircAgtpbp1充当miR-543-5p的分子海绵，调节大鼠垂体细胞中GH的分泌

CircAgtpbp1 Acts as a Molecular Sponge of miR-543-5p to Regulate the Secretion of GH in Rat Pituitary Cells

Animals (Basel).

2.323

吉林大学等

35

环状RNA circ_0021093调节miR-432 / Annexin A2途径以促进肝细胞癌的进展

Circular RNA circ_0021093 regulates miR-432/Annexin A2 pathway to promote hepatocellular carcinoma progression

Anticancer Drugs.

2.26

徐州医科大学附属医院等

36

CircCTNNA1充当miR-363-3p的ceRNA，通过促进CXCL5表达促进结直肠癌的发展

CircCTNNA1 acts as a ceRNA for miR-363-3p to facilitate the progression of colorectal cancer by promoting CXCL5 expression

J Biol Res (Thessalon).

2.121

广东省人民医院等

37

circRNA0006896miR1264DNMT1轴在动脉粥样硬化中通过调节内皮细胞的行为在颈动脉斑块失稳中发挥重要作用

circRNA0006896miR1264DNMT1 axis plays an important role in carotid plaque destabilization by regulating the behavior of endothelial cells in atherosclerosis

Mol Med Rep.

2.1

中山大学附属第八医院等

38

circ0000212通过使miR491变海绵并调节FOXP4表达来促进结直肠癌的细胞增殖

circ0000212 promotes cell proliferation of colorectal cancer by sponging miR491 and modulating FOXP4 expression

Mol Med Rep.

2.1

哈尔滨医科大学第二附属医院等

39

环状RNA在膀胱癌，前列腺癌和肾细胞癌中的功能（综述）

Functions of circular RNAs in bladder, prostate and renal cell cancer (Review)

Mol Med Rep.

2.1

赣南医学院附属第一医院等

40

hsa_circ_0094742的过度表达通过靶向microRNA-127-5p抑制IL-1β诱导的CHON-001细胞活力的下降

Overexpression of hsa_circ_0094742 inhibits IL-1β-induced decline in CHON-001 cell viability by targeting microRNA-127-5p

Histol Histopathol.

2.021

内蒙古医科大学附属第二医院等

41

Circ-AFF2 / miR-650 / CNP轴促进类风湿关节炎滑膜成纤维细胞的增殖、炎症反应、迁移和侵袭

Circ-AFF2/miR-650/CNP axis promotes proliferation, inflammatory response, migration, and invasion of rheumatoid arthritis synovial fibroblasts

J Orthop Surg Res.

1.777

北大医疗淄博医院等

42

CircRNA circ-IQGAP1敲低可通过靶向miR-671-5p / TCF4减轻白介素1β诱导的骨关节炎的进展

CircRNA circ-IQGAP1 Knockdown Alleviates Interleukin-1尾-Induced Osteoarthritis Progression via Targeting miR-671-5p/TCF4

Orthop Surg.

1.718

新疆医科大学附属第一医院等

43

环状RNA circCLK3通过miR-455-5p / PARVA轴促进舌鳞状细胞癌的发展

Circular RNA circCLK3 promotes the progression of tongue squamous cell carcinoma via miR-455-5p/PARVA axis

Biotechnol Appl Biochem.

1.638

淮安市第一人民医院等

44

circRNA_100395在前列腺癌细胞增殖和转移中的抑制作用

Inhibitory role of circRNA_100395 in the proliferation and metastasis of prostate cancer cells

J Int Med Res.

1.287

南方医科大学南方医院等

45

卵清蛋白诱导的变应性鼻炎小鼠模型中环状RNA表达谱的改变

Altered circular RNA expression profiles in an ovalbumin-induced murine model of allergic rhinitis

Allergol Immunopathol (Madr).

1.276

上海交通大学医学院附属上海儿童医学中心等

46

circCUX1通过调节miR-338-3p / PHF20轴促进神经母细胞瘤进展和糖酵解

circCUX1 promotes neuroblastoma progression and glycolysis by regulating the miR-338-3p/PHF20 axis

Gen Physiol Biophys.

1.07

连云港市第一人民医院等

47

血清hsa_circ_0054633升高并与2型糖尿病的临床特征相关

Serum hsa_circ_0054633 Is Elevated and Correlated with Clinical Features in Type 2 Diabetes Mellitus

Ann Clin Lab Sci
.

0.927

宁夏医科大学总医院等

48

轻、重度流感相关肺炎患者外周血单个核细胞中circRNA的表达差异

[Differential circRNA expression profiles in peripheral blood mononuclear cells among mild and severe influenza-associated pneumonia patients]

Zhonghua Yi Xue Za Zhi

0

北京朝阳医院等

49

化学合成带有磷酸氨基磷酸酯键的环状RNA，用于滚环翻译

Chemical Synthesis of Circular RNAs with Phosphoramidate Linkages for Rolling-Circle Translation

Curr Protoc

0

日本名古屋大学等